ea0002p71 | Neuroendocrinology | SFE2001
Coculescu M
, Badiu C
, Caragheorgheopol A
, Gheorghiu M
, Gussi I
, Radian S
, Rotarus R
, Carnu R
, Rasanu C
, Braga R
There are difficulties in establishing the diagnosis of gonadotropinomas using serum hormonal levels, even after intravenous TRH. We evaluated the relationship between humoral (serum and cerebrospinal fluid - CSF) levels of gonadotropins and the immunohistochemical evidence in tumor tissue.Serum and CSF levels of pituitary hormones were assayed using rapid fluoroimmunometry with Europium. Immunohistochemistry (IHC) was performed with avidin-biotine. Grou...